Eigenschaften/Wirkungen: is an oral, direct factor Xa inhibitor with good bioavailability, low potential for drug-drug interactions, and a half-life of approximately 12 h. It has a high affinity for factor Xa and inhibits free factor Xa, factor Xa in the prothrombinase complex, and factor Xa bound to platelets (1). Pharmakokinetik: it is eliminated via multiple pathways, predominantly via the fecal route (56%), with 25–29% of the recovered dose eliminated via urinary excretion (1). Referenzen: |
NIRCO med‎ > ‎drugs‎ > ‎Antithrombotika‎ > ‎Faktor-Xa-Inhibitoren‎ > ‎direkte‎ > ‎