Eigenschaften/Wirkungen:

• Three classes of antiemetic drugs, serotonin antagonists (e.g. ondansetron), corticosteroids (e.g. dexamethasone), and dopamine antagonists (e.g. droperidol) have similar efficacy against postoperative nausea and vomiting, with a relative risk reduction of ~25%. Moreover, they act independently and, when used in combination, have additive effects (1).
• Three other serotonin antagonists, namely granisetron, dolasetron, and palonosetron, have a similar efficacy and side-effect profile (e.g. constipation, headache) to ondansetron (1).
  

Referenzen:

1. Medscape Anesthesiology - MedPulse Newsletter: Nausea and Vomiting after surgery. 30/04/2013.